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KMID : 0363320190400010038
Journal of Korean Oriental Internal Medicine
2019 Volume.40 No. 1 p.38 ~ p.57
Review of Clinical Research about Herbal Medicine Treatment Containing Diuretic Herbs on Non-Alcoholic Fatty Liver Disease - Research on China Academic Journal
Kim Young-Kwang

Jo Myoung-Jae
Moon Young-Ho
Abstract
Objective: This study reviewed recent clinical research trends regarding the effects of herbal medicine treatment containing diuretic herbs on nonalcoholic fatty liver disease (NAFLD) in China.

Methods: We reviewed clinical studies on NAFLD from the China Academic Journal of the China National Knowledge Infrastructure from January 1, 2016, to September 10, 2018.

Results: Thirty-nine papers from 86 studies were reviewed. The most commonly used herbal prescriptions included Alismatis Rhizoma (÷ÊÞá), Salviae miltiorrhizae Radix (ӡ߸), Crataegii Fructus (ߣÞÛ), Polia Sclerotium (ÜÚ?), Bupleuri Radix (ãÃû×), and Cassiae Semen (̽٥í­). The treatment effective rate, liver function test, serum lipid test, radiological examination, and symptom comparisons were used to analyze the treatments. In 32 of the papers, the effective treatment rate was 76.9%-100%, and the effectiveness in the experimental group was significantly higher than that in the control group (p<0.05). The risk ratio for the treatment effective rate was 1.26. The mean difference of ALT was -13.44 U/L (95% confidential interval, -24.45 U/L, -2.44 U/L, p=0.0166).

Conclusion: Herbal medicine containing diuretic herbs has been demonstrated to be an effective and useful treatment for NAFLD. Clinical studies that are more scientific and systematic should be actively conducted in the future, and the results of the current study could be used as basic data in future clinical studies on herbal medicine treatment for NAFLD.
KEYWORD
rbal medicine treatment, diutretic herbs, traditional Chinese medicine, NAFLD, CAJ
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